.. meta::
   :description: AMD Instinct MI350 Series microarchitecture reference.
   :keywords: Instinct, MI350X, MI355X, CDNA4, microarchitecture, AMD, ROCm

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AMD Instinct MI350 Series microarchitecture
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This section covers the AMD Instinct MI350 Series GPU architecture based on AMD
CDNA4. It includes the following topics:

* `AMD CDNA 4 (Instinct MI350 Series) ISA reference <https://www.amd.com/content/dam/amd/en/documents/instinct-tech-docs/instruction-set-architectures/amd-instinct-cdna4-instruction-set-architecture.pdf>`_ --
  Instruction set architecture reference for the AMD Instinct MI350 Series.

* `White paper <https://www.amd.com/content/dam/amd/en/documents/instinct-tech-docs/white-papers/amd-cdna-4-architecture-whitepaper.pdf>`_ --
  Architectural overview of the AMD CDNA 4 design.

* :doc:`MI350 Series performance counters <mi350-performance-counters>` --
  Hardware performance counters and derived metrics available for profiling
  MI350 Series GPUs using ROCprofiler-SDK and ROCm Compute Profiler.
